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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FER All Species: 23.94
Human Site: S427 Identified Species: 47.88
UniProt: P16591 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16591 NP_005237.2 822 94638 S427 K F E S I R H S I A G I I R S
Chimpanzee Pan troglodytes XP_517863 822 94653 S427 K F E S I R H S I A G I I R S
Rhesus Macaque Macaca mulatta XP_001099988 808 93284 S427 K F E S I R H S I A G I I R S
Dog Lupus familis XP_851836 820 93016 L425 R T P T L E I L K S H I S G I
Cat Felis silvestris
Mouse Mus musculus P70451 823 94560 S427 K F E S I R H S I A G I I K S
Rat Rattus norvegicus P09760 323 37086
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512215 821 94492 S426 K F D T L R H S I A G M I R S
Chicken Gallus gallus P00523 533 59991 V174 N P R G T F L V R E S E T T K
Frog Xenopus laevis P13116 532 59718 V173 N P R G T F L V R E S E T T K
Zebra Danio Brachydanio rerio XP_693576 842 96630 S434 K F D T L R H S I A G I I R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18106 1325 150245 S927 E E E E D S A S D D V L S M K
Honey Bee Apis mellifera XP_623692 782 90822 I407 P S I S K L Q I L G N G N G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 95.1 51.4 N.A. 92.9 36.2 N.A. 88.6 24.9 25.1 73.5 N.A. 28 40 N.A. N.A.
Protein Similarity: 100 99.8 96.7 70 N.A. 96.8 37.9 N.A. 95.1 38.6 39.5 85.3 N.A. 43.4 61.3 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 0 N.A. 73.3 0 0 80 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 0 N.A. 100 0 0 100 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 50 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 0 9 0 0 0 9 9 0 0 0 0 0 % D
% Glu: 9 9 42 9 0 9 0 0 0 17 0 17 0 0 0 % E
% Phe: 0 50 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 0 0 0 0 0 9 50 9 0 17 9 % G
% His: 0 0 0 0 0 0 50 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 34 0 9 9 50 0 0 50 50 0 9 % I
% Lys: 50 0 0 0 9 0 0 0 9 0 0 0 0 9 25 % K
% Leu: 0 0 0 0 25 9 17 9 9 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % M
% Asn: 17 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 9 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 17 0 0 50 0 0 17 0 0 0 0 42 0 % R
% Ser: 0 9 0 42 0 9 0 59 0 9 17 0 17 0 50 % S
% Thr: 0 9 0 25 17 0 0 0 0 0 0 0 17 17 0 % T
% Val: 0 0 0 0 0 0 0 17 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _